Found 48 of ec50 data for polymerid = 2124,3139 
Affinity DataEC50: 0.100nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig illeum assessed as electric field-stimulated responseMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig illeum assessed as electric field-stimulated responseMore data for this Ligand-Target Pair
Affinity DataEC50: 0.220nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig illeum assessed as electric field-stimulated responseMore data for this Ligand-Target Pair
Affinity DataEC50: 0.390nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 0.390nMAssay Description:Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at GFP-tagged rat kappa opioid receptor expressed in HEK293 cells assessed as increase in ERK1/2 phosphorylation after 5 mins by Wes...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 0.540nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 0.650nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 1.24nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 3.56nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 4.19nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 5.10nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Agonist activity at GFP-tagged rat kappa opioid receptor expressed in HEK293 cells assessed as increase in beta-arrestin mediated p38 phosphorylation...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Effective concentration to inhibit E203Q,D204N,D206N KL-2 Opioid receptor kappa 1 binding to [35S]GTP-gamma-S, expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 7.70nMAssay Description:Agonist activity at rat kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.90nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Effective concentration to inhibit D216,ND217N,E218Q KL-2 Opioid receptor kappa 1 binding to [35S]GTP-gamma-S, expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 8.30nMAssay Description:Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Effective concentration to inhibit wild type KL-2 Opioid receptor kappa 1 binding to [35S]GTP-gamma-S, expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Binding affinity towards k-opioid receptor k-EL-2 mutant (wild-type) expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at KOR in guinea pig vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataEC50: 29.4nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 36.5nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 46.9nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 72.4nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 153nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 205nMAssay Description:Agonist activity at rat kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 480nMAssay Description:Agonist activity at rat kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 515nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 573nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 955nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataEC50: 1.35E+3nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataEC50: 1.45E+3nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+3nMAssay Description:Agonist activity at kappa opioid receptor guinea pig colon tissueMore data for this Ligand-Target Pair
Affinity DataEC50: 1.86E+3nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataEC50: <7.94E+3nMAssay Description:Agonist activity at rat KOR expressed in CHOK1 cells assessed as increase in cAMP accumulation measured after 10 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 9.55E+3nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at rat KOR expressed in CHOK1 cells assessed as increase in cAMP accumulation measured after 10 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at rat KOR expressed in CHOK1 cells assessed as increase in cAMP accumulation measured after 10 mins by HTRF assayMore data for this Ligand-Target Pair
